Preparation and characterization of fenofibrate-loaded zeolitic imidazolate frameworks and their evaluation in dissolution enhancement of the formulation

The purpose of this study was to develop zeolitic imidazolate frameworks (ZIFs) incorporated with poorly water-soluble drug fenofibrate (FEN), belonging to Biopharmaceutical Classification System (BCS) class II, to improve drug dissolution, intended to be orally administrated. FEN-loaded ZIF-8 were...

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Bibliographic Details

Published in:	شیمی کاربردی روز
Main Authors:	Aziz maleki, Ziba Islambulchilar, Roya Poornorouz, Mehrdad Hamidi, Masoumeh Kord, Mohammad Ali Shahbazi
Format:	Article
Language:	English
Published:	Semnan University 2021-06-01
Subjects:	fenofibrate dissolution rate poorly water-soluble drug zeolitic imidazolate frameworks zif-8
Online Access:	https://chemistry.semnan.ac.ir/article_5257_5edb080640558ac8c10ddd6636b5e460.pdf