Long-term haplodeficency of DSPP causes temporomandibular joint osteoarthritis in mice

Abstract Background Extracellular matrix (ECM) protein malfunction or defect may lead to temporomandibular joint osteoarthritis (TMJ OA). Dentin sialophophoprotein (DSPP) is a mandibular condylar cartilage ECM protein, and its deletion impacted cell proliferation and other extracellular matrix alter...

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Bibliographic Details
Published in:BMC Oral Health
Main Authors: Qilin Liu, Yitong Zhao, Haibo Shi, Danwei Xiang, Chunye Wu, Lina Song, Ning Ma, Hongchen Sun
Format: Article
Language:English
Published: BMC 2024-05-01
Subjects:
Temporomandibular joint
Osteoarthritis
Mandibular condylar cartilage
Subchondral bone
Dentin sialophosphoprotein
Knockout mice
Online Access:https://doi.org/10.1186/s12903-024-04320-8

Internet

https://doi.org/10.1186/s12903-024-04320-8

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