The use of temozolomide in paediatric metastatic phaeochromocytoma/paraganglioma: A case report and literature review

There is increasing evidence to support the use of temozolomide therapy for the treatment of metastatic phaeochromocytoma/paraganglioma (PPGL) in adults, particularly in patients with SDHx mutations. In children however, very little data is available. In this report, we present the case of a 12-year...

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Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Calum Urquhart, Ben Fleming, Ines Harper, Luigi Aloj, Ruth Armstrong, Liz Hook, Anna-May Long, Claire Jackson, Ferdia A. Gallagher, Mary A. McLean, Patrick Tarpey, Vasilis Kosmoliaptsis, James Nicholson, A. Emile J. Hendriks, Ruth T. Casey
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-11-01
Subjects:	paraganglioma pheochromocytoma temozolomide succinate dehydrogenase (SDH) SDHB = SDH enzyme complex subunit B
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2022.1066208/full