[PROVISIONAL] The combined risk effect among BIN1, CLU and APOE genes in Alzheimer’s disease

Abstract Genome-wide associations studies (GWAS) have been detecting new variants associated with late-onset of Alzheimer’s disease (LOAD), a multifactorial neurodegenerative disorder. The variants rs744373 BIN1, rs11136000 CLU rs3764650 ABCA7 uncovered by GWAS led to different AD pathways, such as...

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Bibliographic Details
Published in:Genetics and Molecular Biology
Main Authors: Lígia Ramos dos Santos, Jucimara Ferreira Figueiredo Almeida, Lúcia Helena Sagrillo Pimassoni, Renato Lírio Morelato, Flavia de Paula
Format: Article
Language:English
Published: Sociedade Brasileira de Genética
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572019005040102&lng=en&tlng=en