HBV activates hepatic stellate cells through RUNX2/ITGBL1 axis

Abstract Background Chronic hepatitis B (CHB) remains a global health challenge, with liver fibrosis serving as a critical determinant of disease progression. Despite antiviral treatments, liver fibrosis often persists in CHB patients, highlighting the need for additional biomarkers and therapeutic...

Full description

Bibliographic Details

Published in:	Virology Journal
Main Authors:	Fengchun Shi, Wei Tan, Wei Huang, Fei Ye, Mingjie Wang, Yongxiang Wang, Xinxin Zhang, Demin Yu
Format:	Article
Language:	English
Published:	BMC 2025-04-01
Subjects:	Chronic hepatitis B RUNX2 ITGBL1 Liver fibrosis
Online Access:	https://doi.org/10.1186/s12985-025-02749-z