Extracellular-superoxide dismutase DNA methylation promotes oxidative stress in homocysteine-induced atherosclerosis

In the present study, we investigate the effect of homocysteine (Hcy) on extracellular-superoxide dismutase (EC-SOD) DNA methylation in the aorta of mice, and explore the underlying mechanism in macrophages, trying to identify the key targets of Hcy-induced EC-SOD methylation changes....

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Bibliographic Details

Published in:	Acta Biochimica et Biophysica Sinica
Main Authors:	Ma Shengchao, Lu Guanjun, Zhang Qing, Ding Ning, Jie Yuzhen, Zhang Hui, Xu Lingbo, Xie Lin, Yang Xiaoling, Zhang Huiping, Jiang Yideng
Format:	Article
Language:	English
Published:	China Science Publishing & Media Ltd. 2022-07-01
Subjects:	homocysteine oxidative stress extracellular-superoxide dismutase DNA methylation
Online Access:	https://www.sciengine.com/doi/10.3724/abbs.2022093