Paclitaxel resistance development is associated with biphasic changes in reactive oxygen species, mitochondrial membrane potential and autophagy with elevated energy production capacity in lung cancer cells: A chronological study

Paclitaxel (Tx) is one of the first-line chemotherapeutic drugs used against lung cancer, but acquired resistance to this drug is a major challenge against successful chemotherapy. In this work, we have focused on the chronological changes of various cellular parameters and associated effect on Tx (...

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Bibliographic Details
Published in:Tumor Biology
Main Authors: Satabdi Datta, Diptiman Choudhury, Amlan Das, Dipanwita Das Mukherjee, Nabanita Das, Sib Sankar Roy, Gopal Chakrabarti
Format: Article
Language:English
Published: SAGE Publishing 2017-02-01
Online Access:https://doi.org/10.1177/1010428317694314