Apigenin Alleviates Liver Fibrosis by Inhibiting Hepatic Stellate Cell Activation and Autophagy via TGF-β1/Smad3 and p38/PPARα Pathways

Objective. The aim of this study is to confirm the hepatocellular protective functions of apigenin and the molecular mechanism on liver fibrosis in mice. Methods. Carbon tetrachloride (CCl4) and bile duct ligature (BDL) mouse fibrosis models were used to investigate the effects of apigenin on liver...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:PPAR Research
المؤلفون الرئيسيون: Jie Ji, Qiang Yu, Weiqi Dai, Liwei Wu, Jiao Feng, Yuanyuan Zheng, Yan Li, Chuanyong Guo
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Wiley 2021-01-01
الوصول للمادة أونلاين:http://dx.doi.org/10.1155/2021/6651839