Development of an ostrich-derived single-chain variable fragment (scFv) against PTPRN extracellular domain

Abstract In type 1 diabetes, the immune system destroys pancreatic beta cells in an autoimmune condition. To overcome this disease, a specific monoclonal antibody that binds to pancreatic beta cells could be used for targeted immunotherapy. Protein tyrosine phosphatase receptor N (PTPRN) is one of t...

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書誌詳細

出版年:	Scientific Reports
主要な著者:	Hamed Dabiri, Majid Sadeghizadeh, Vahab Ziaei, Zahra Moghadasi, Ali Maham, Ensiyeh Hajizadeh-Saffar, Mahdi Habibi-Anbouhi
フォーマット:	論文
言語:	英語
出版事項:	Nature Portfolio 2024-02-01
オンライン･アクセス:	https://doi.org/10.1038/s41598-024-53386-5