Analysis of global DNA methylation and epigenetic modifiers (DNMTs and HDACs) in human foetal endothelium exposed to gestational and type 2 diabetes

Foetuses exposed to maternal gestational diabetes (GDM) and type 2 diabetes (T2D) have an increased risk of adverse perinatal outcomes. Epigenetic mechanisms, including DNA methylation and histone modifications, may act as mediators of persistent metabolic memory in endothelial cells (ECs) exposed t...

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Bibliographic Details
Published in:Epigenetics
Main Authors: Samar Sultan, Sultanh AlMalki
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Subjects:
endothelial cells
gestational diabetes
type 2 diabetes
dna methylation
epigenetic enzymes
Online Access:http://dx.doi.org/10.1080/15592294.2023.2201714

Internet

http://dx.doi.org/10.1080/15592294.2023.2201714

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