Baicalin promotes the sensitivity of NSCLC to cisplatin by regulating ferritinophagy and macrophage immunity through the KEAP1-NRF2/HO-1 pathway

Abstract Background Cisplatin (DDP) chemotherapy is commonly used in therapy for non-small cell lung cancer (NSCLC), but increased drug resistance has become a huge obstacle. Baicalin (BA) contributed to the sensitivity of NSCLC to DDP. Here, we aimed to further probe the pathophysiological mechanis...

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Bibliographic Details

Published in:	European Journal of Medical Research
Main Authors:	Yang Chen, Shujun Bao, Zhongzhao Wang, Zheng Fang, Hao Tang
Format:	Article
Language:	English
Published:	BMC 2024-07-01
Subjects:	Baicalin (BA) KEAP1-NRF2/HO-1 Non-small cell lung cancer (NSCLC) Cisplatin (DDP)
Online Access:	https://doi.org/10.1186/s40001-024-01930-4