Taurine alleviates hyperuricemia-induced nephropathy in rats: insights from microbiome and metabolomics

BackgroundGut microbiota play a critical role in developing hyperuricemic nephropathy (HN). We previously found that sulfur-containing amino acid taurine (T) has nephroprotective effects in hyperuricemia (HUA) rats. However, the mechanism is still unclear. To investigate the underlying mechanism of...

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Bibliographic Details

Published in:	Frontiers in Nutrition
Main Authors:	Xiujuan Yang, Hengxi Li, Daermu Qumu, Binhui Han, Mukaram Amatjan, Qiyao Wu, Lanting Wei, Bo Li, Mengxue Ma, Junjie He, San Wang, Yingzhi Yu, Xiaoni Shao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Subjects:	taurine hyperuricemia nephropathy gut microbiota metabolomics
Online Access:	https://www.frontiersin.org/articles/10.3389/fnut.2025.1587198/full