CD68 as a multi-omic prognostic biomarker in digestive system cancers: correlations with tumor-infiltrating immune cells and immune checkpoints

Background and objectiveCD68 plays a crucial role in promoting phagocytosis. However, its expression level, prognostic value and the correlations with tumor-infiltrating immune cells (TIICs) or common tumor immune checkpoints (TICs) in human digestive system cancers (DSC) remain poorly understood. T...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Hui Li, Hui Zhang, Rujiang Dai, Dian Zheng, Jianghai Zhao, Hong Jing, Xuhui Ma, Lin Zhang, Weihong Sun, Zhimin Suo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-08-01
Subjects:	CD68 digestive system cancers macrophage prognosis biomarker immune checkpoint
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1599677/full