Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain

Abstract Background Altered intestinal microbiota composition in later life is associated with inflammaging, declining tissue function, and increased susceptibility to age-associated chronic diseases, including neurodegenerative dementias. Here, we tested the hypothesis that manipulating the intesti...

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發表在:	Microbiome
Main Authors:	Aimée Parker, Stefano Romano, Rebecca Ansorge, Asmaa Aboelnour, Gwenaelle Le Gall, George M. Savva, Matthew G. Pontifex, Andrea Telatin, David Baker, Emily Jones, David Vauzour, Steven Rudder, L. Ashley Blackshaw, Glen Jeffery, Simon R. Carding
格式:	Article
語言:	英语
出版:	BMC 2022-04-01
主題:	Aging Microbiota Gut–brain axis Gut–retina Intestine Fecal microbiota transplantation
在線閱讀:	https://doi.org/10.1186/s40168-022-01243-w