Next-generation sequencing-based genomic profiling of advanced soft tissue and bone sarcomas

BackgroundSarcomas are rare mesenchymal tumors classified into soft tissue (STS) and bone sarcomas. Despite advances in treatment, the 5-year survival rate for metastatic disease remains low. There is still limited evidence regarding the use of next-generation sequencing (NGS).AimTo identify targeta...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Yasemin Gündoğdu, Elif Şenocak Taşçı, Leyla Özer, Can Boynukara, Recep Çeçen, Arda Ulaş Mutlu, İbrahim Yıldız
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-10-01
Subjects:	sarcoma soft tissue next-generation sequencing molecular targeted therapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1627452/full