Trophectoderm Transcriptome Analysis in LIN28 Knockdown Ovine Conceptuses Suggests Diverse Roles of the LIN28-let-7 Axis in Placental and Fetal Development

The proper conceptus elongation in ruminants is critical for the successful placentation and establishment of pregnancy. We have previously shown that the trophectoderm-specific knockdown of LIN28A/B in day 9 ovine blastocysts resulted in increased let-7 miRNAs and reduced conceptus elongation at da...

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Bibliographic Details

Published in:	Cells
Main Authors:	Asghar Ali, Muhammad A. Iqbal, Muhammad W. Abbas, Gerrit J. Bouma, Russell V. Anthony, Thomas E. Spencer, Quinton A. Winger
Format:	Article
Language:	English
Published:	MDPI AG 2022-04-01
Subjects:	microRNAs blastocyst RNA sequencing LIN28A LIN28B fetal growth
Online Access:	https://www.mdpi.com/2073-4409/11/7/1234