A Microdialysis in Adjuvant Arthritic Rats for Pharmacokinetics–Pharmacodynamics Modeling Study of Geniposide with Determination of Drug Concentration and Efficacy Levels in Dialysate

Microdialysis, a sampling method for pharmacokinetics–pharmacodynamics (PK–PD) modeling in preclinical and clinical studies, is a convenient in vivo sampling technique. Geniposide (GE), an iridoid glycoside compound, is the major active ingredient of Gardenia jasminoides Ellis fruit which has an ant...

詳細記述

書誌詳細

出版年:	Molecules
主要な著者:	Ran Deng, Wei Wang, Hong Wu, Yunjing Zhang, Wenyu Wang, Li Dai, Zhengrong Zhang, Jun Fu, Feng Li
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2018-04-01
主題:	rheumatoid arthritis microdialysis geniposide PK–PD modeling prostaglandin E2 UHPLC-MS/MS
オンライン･アクセス:	http://www.mdpi.com/1420-3049/23/5/987