Comparative effectiveness of an individualized model of hemodialysis vs conventional hemodialysis: a study protocol for a multicenter randomized controlled trial (the TwoPlus trial)

Abstract Background Most patients starting chronic in-center hemodialysis (HD) receive conventional hemodialysis (CHD) with three sessions per week targeting specific biochemical clearance. Observational studies suggest that patients with residual kidney function can safely be treated with increment...

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Bibliographic Details

Published in:	Trials
Main Authors:	Mariana Murea, Jochen G. Raimann, Jasmin Divers, Harvey Maute, Cassandra Kovach, Emaad M. Abdel-Rahman, Alaa S. Awad, Jennifer E. Flythe, Samir C. Gautam, Vandana D. Niyyar, Glenda V. Roberts, Nichole M. Jefferson, Islam Shahidul, Ucheoma Nwaozuru, Kristie L. Foley, Erica J. Trembath, Merlo L. Rosales, Alison J. Fletcher, Sheikh I. Hiba, Anne Huml, Daphne H. Knicely, Irtiza Hasan, Bhaktidevi Makadia, Raman Gaurav, Janice Lea, Paul T. Conway, John T. Daugirdas, Peter Kotanko, on behalf of the Two Plus Research Consortium
Format:	Article
Language:	English
Published:	BMC 2024-06-01
Subjects:	End-stage kidney disease Hemodialysis Incremental Randomized controlled trial
Online Access:	https://doi.org/10.1186/s13063-024-08281-9