Comparative transcriptome analysis of T lymphocyte subpopulations and identification of critical regulators defining porcine thymocyte identity

IntroductionThe development and migration of T cells in the thymus and peripheral tissues are crucial for maintaining adaptive immunity in mammals. However, the regulatory mechanisms underlying T cell development and thymocyte identity formation in pigs remain largely underexplored. MethodHere, by i...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Pingping Han, Wei Zhang, Daoyuan Wang, Yalan Wu, Xinyun Li, Shuhong Zhao, Mengjin Zhu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-02-01
Subjects:	comparative transcriptome T cell development co-expression analysis gene regulatory network transcription factor GWAS
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1339787/full