Inflammation-activated C/EBPβ mediates high-fat diet-induced depression-like behaviors in mice

Depression, one of the most common causes of disability, has a high prevalence rate in patients with metabolic syndrome. Type 2 diabetes patients are at an increased risk for depression. However, the molecular mechanism coupling diabetes to depressive disorder remains largely unknown. Here we found...

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Bibliographic Details

Published in:	Frontiers in Molecular Neuroscience
Main Authors:	Yiyi Li, Hongyu Chen, Jianhao Wang, Jiabei Wang, Xuan Niu, Chao Wang, Dongdong Qin, Fang Li, Yamei Wang, Jing Xiong, Songyan Liu, Liqin Huang, Xi Zhang, Feng Gao, Dandan Gao, Mingxia Fan, Xuan Xiao, Zhi-Hao Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-12-01
Subjects:	high-fat diet depression transcription factor C/EBPβ inflammation BDNF
Online Access:	https://www.frontiersin.org/articles/10.3389/fnmol.2022.1068164/full