Age-related changes in the immune system and challenges for the development of age-specific vaccines

Background A better understanding of how the immune system evolves with age and how vaccines work in older people has led to increasing focus on the development of vaccines aimed specifically at older age groups. We discuss strategies used to improve vaccine immunogenicity for older adults, focusing...

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Bibliographic Details

Published in:	Annals of Medicine
Main Authors:	T. Mark Doherty, Birgit Weinberger, Arnaud Didierlaurent, Paul-Henri Lambert
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2025-12-01
Subjects:	Vaccine older adults immunosenescence inflammaging adjuvant Adjuvant system
Online Access:	https://www.tandfonline.com/doi/10.1080/07853890.2025.2477300