Population-based analysis of ocular Chlamydia trachomatis in trachoma-endemic West African communities identifies genomic markers of disease severity

Abstract Background Chlamydia trachomatis (Ct) is the most common infectious cause of blindness and bacterial sexually transmitted infection worldwide. Ct strain-specific differences in clinical trachoma suggest that genetic polymorphisms in Ct may contribute to the observed variability in severity...

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الحاوية / القاعدة:	Genome Medicine
المؤلفون الرئيسيون:	A. R. Last, H. Pickering, C. h. Roberts, F. Coll, J. Phelan, S. E. Burr, E. Cassama, M. Nabicassa, H. M. B. Seth-Smith, J. Hadfield, L. T. Cutcliffe, I. N. Clarke, D. C. W. Mabey, R. L. Bailey, T. G. Clark, N. R. Thomson, M. J. Holland
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	BMC 2018-02-01
الموضوعات:	Chlamydia trachomatis Trachoma Disease severity Genome-wide association analysis Single nucleotide polymorphisms Pathogen genomic diversity
الوصول للمادة أونلاين:	http://link.springer.com/article/10.1186/s13073-018-0521-x