Differential Activities of the Botanical Extract PBI-05204 and Oleandrin on Innate Immune Functions under Viral Challenge Versus Inflammatory Culture Conditions

The <i>Nerium oleander</i> extract PBI 05204 (PBI) and its cardiac glycoside constituent oleandrin have direct anti-viral properties. Their effect on the immune system, however, is largely unknown. We used an in vitro model of human peripheral blood mononuclear cells to document effects...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Gitte S. Jensen, Liu Yu, Ifeanyi Iloba, Dina Cruickshank, Jose R. Matos, Robert A. Newman
Format:	Article
Language:	English
Published:	MDPI AG 2023-06-01
Subjects:	anti-inflammatory CD25 CD69 CD107a immune-modulation interferon-gamma
Online Access:	https://www.mdpi.com/1420-3049/28/12/4799