The Screening of Broadly Neutralizing Antibodies Targeting the SARS-CoV-2 Spike Protein by mRNA Immunization in Mice

Neutralizing antibodies (nAbs), the popular antiviral drugs used for the treatment of COVID-19, are effective in reducing viral load and hospitalization. Currently, most nAbs are screened from convalescent or vaccinated individuals through single B-cell sequencing which requires cutting-edge facilit...

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Bibliographic Details

Published in:	Pharmaceutics
Main Authors:	Zhiyin An, Yu Zhang, Xiang Yu, Jia Xia, Yanan Yin, Guoming Li, Jing Lu, Xuemei Fan, Yingjie Xu
Format:	Article
Language:	English
Published:	MDPI AG 2023-05-01
Subjects:	SARS-CoV-2 spike mRNA vaccine broadly neutralizing antibody
Online Access:	https://www.mdpi.com/1999-4923/15/5/1412