Engineering of Burkholderia thailandensis strain E264 serves as a chassis for expression of complex specialized metabolites

Heterologous expression is an indispensable approach to exploiting natural products from phylogenetically diverse microbial communities. In this study, we constructed a heterologous expression system based on strain Burkholderia thailandensis E264 by deleting efflux pump genes and screening constitu...

Full description

Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Zong-Jie Wang, Xiaotong Liu, Haibo Zhou, Yang Liu, Lin Zhong, Xue Wang, Qiang Tu, Liujie Huo, Fu Yan, Lichuan Gu, Rolf Müller, Youming Zhang, Xiaoying Bian, Xiaokun Xu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-11-01
Subjects:	Burkholderia chassis heterologous expression disorazol rhizoxin
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2022.1073243/full