Acetylsalicylic acid aggravates anaphylaxis in a PGE2-dependent manner

Acetylsalicylic acid (ASA) can exert proanaphylactic effects, but the extent of this phenomenon and its underlying mechanisms are undefined. Yet, low homeostatic prostaglandin E2 (PGE2) levels have been associated with anaphylaxis. In this study, we investigated whether the proanaphylactic effect of...

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Bibliographic Details
Published in:The Journal of Clinical Investigation
Main Authors: Philipp Globig, Payam Morakabati, Veronika Höfer, Diana M. Willmes, Magda Babina, Margitta Worm
Format: Article
Language:English
Published: American Society for Clinical Investigation 2025-03-01
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Online Access:https://doi.org/10.1172/JCI175397