Anti-Tumor Effects of Engineered VNP20009-Abvec-Igκ-mPD-1 Strain in Melanoma Mice via Combining the Oncolytic Therapy and Immunotherapy

Programmed cell death protein 1/Programmed cell death ligand 1 (PD-1/PD-L1) immune checkpoint inhibitors are the most promising treatments for malignant tumors currently, but the low response rate limits their further clinical utilization. To address this problem, our group constructed an engineered...

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Bibliographic Details

Published in:	Pharmaceutics
Main Authors:	De-Xi Zhou, Xiao-He Wang, Xuan Xu, Wen-Jie Chen, Jing Wei, Ting-Tao Chen, Hong Wei
Format:	Article
Language:	English
Published:	MDPI AG 2022-12-01
Subjects:	VNP20009 mPD-1 bacterial therapy melanoma
Online Access:	https://www.mdpi.com/1999-4923/14/12/2789