HBV Precore G1896A Mutation Promotes Malignancy of Hepatocellular Carcinoma by Activating Endoplasmic Reticulum Stress to Enhance Aerobic Glycolysis

ABSTRACT Hepatitis B virus (HBV) precore G1896A mutation is closely associated with poor prognosis of liver disease. We previously revealed that the G1896A mutation could enhance HBV replication and promote hepatocellular carcinoma (HCC) cell growth both in vitro and in vivo. However, the in‐depth m...

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Bibliographic Details

Published in:	MedComm
Main Authors:	Baoxin Zhao, Hongxiu Qiao, Zhiyun Gao, Yan Zhao, Weijie Wang, Yan Cui, Fangxu Li, Yuping Wang, Zhanjun Guo, Xia Chuai, Sandra Chiu
Format:	Article
Language:	English
Published:	Wiley 2025-09-01
Subjects:	aerobic glycolysis endoplasmic reticulum stress HBV G1896A mutation hepatocellular carcinoma
Online Access:	https://doi.org/10.1002/mco2.70365