A fluorogenic substrate for the detection of lipid amidases in intact cells

Lipid amidases of therapeutic relevance include acid ceramidase (AC), N-acylethanolamine-hydrolyzing acid amidase, and fatty acid amide hydrolase (FAAH). Although fluorogenic substrates have been developed for the three enzymes and high-throughput methods for screening have been reported, a platform...

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Bibliographic Details

Published in:	Journal of Lipid Research
Main Authors:	Mireia Casasampere, Johnson Ung, Alejandro Iñáñez, Carine Dufau, Kazuhito Tsuboi, Josefina Casas, Su-Fern Tan, David J. Feith, Nathalie Andrieu-Abadie, Bruno Segui, Thomas P. Loughran, Jr., José Luis Abad, Gemma Fabrias
Format:	Article
Language:	English
Published:	Elsevier 2024-03-01
Subjects:	sphingolipids ceramides lipids enzymology chemical synthesis N-palmitoylethanolamine
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227524000257