Is a rare CXCL8 gene variant a new possible cause or course factor of inflammatory bowel disease?

IntroductionThe pathogenesis of inflammatory bowel diseases (IBD) involves genetic, environmental, immunological, and microbial factors; however, it remains unclear. Pro-inflammatory interleukin 8 (IL-8), encoded by the CXCL8 gene, assumes a crucial chemotactic role in leukocyte migration.MethodsThi...

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書誌詳細

出版年:	Frontiers in Immunology
主要な著者:	Marcin Gabryel, Oliwia Zakerska-Banaszak, Karolina Ladziak, Katarzyna Anna Hubert, Alina Baturo, Joanna Suszynska-Zajczyk, Magdalena Hryhorowicz, Agnieszka Dobrowolska, Marzena Skrzypczak-Zielinska
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2025-03-01
主題:	CXCL8 gene inflammatory bowel disease (IBD) inflammation interleukin 8 genetic variants Crohn’s disease
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1562618/full