Anti-Sca-1 antibody-functionalized vascular grafts improve vascular regeneration via selective capture of endogenous vascular stem/progenitor cells

Small-diameter vascular grafts fabricated from synthetic biodegradable polymers exhibit beneficial mechanical properties but often face poor regenerative potential. Different tissue engineering approaches have been employed to improve tissue regeneration in vascular grafts, but there remains a requi...

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Bibliographic Details

Published in:	Bioactive Materials
Main Authors:	He Wang, Mengmeng Xing, Weiliang Deng, Meng Qian, Fei Wang, Kai Wang, Adam C. Midgley, Qiang Zhao
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2022-10-01
Subjects:	Small-diameter vascular grafts Surface modification Stem cell antigen-1 (Sca-1) antibody Vascular stem/progenitor cells (SPCs) Tissue regeneration
Online Access:	http://www.sciencedirect.com/science/article/pii/S2452199X22001232