Credibility Evidence for Computational Patient Models Used in the Development of Physiological Closed-Loop Controlled Devices for Critical Care Medicine

Physiological closed-loop controlled medical devices automatically adjust therapy delivered to a patient to adjust a measured physiological variable. In critical care scenarios, these types of devices could automate, for example, fluid resuscitation, drug delivery, mechanical ventilation, and/or ane...

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Bibliographic Details

Published in:	Frontiers in Physiology
Main Authors:	Bahram Parvinian, Pras Pathmanathan, Chathuri Daluwatte, Farid Yaghouby, Richard A. Gray, Sandy Weininger, Tina M. Morrison, Christopher G. Scully
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-03-01
Subjects:	mathematical physiological model computational modeling and simulation testing physiologic closed-loop control systems model credibility evidence medical devices
Online Access:	https://www.frontiersin.org/article/10.3389/fphys.2019.00220/full