Gut-first Parkinson’s disease is encoded by gut dysbiome

Abstract Background In Parkinson's patients, intestinal dysbiosis can occur years before clinical diagnosis, implicating the gut and its microbiota in the disease. Recent evidence suggests the gut microbiota may trigger body-first Parkinson Disease (PD), yet the underlying mechanisms remain unc...

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Bibliographic Details
Published in:Molecular Neurodegeneration
Main Authors: Mário F. Munoz-Pinto, Emanuel Candeias, Inês Melo-Marques, A. Raquel Esteves, Ana Maranha, João D. Magalhães, Diogo Reis Carneiro, Mariana Sant’Anna, A. Raquel Pereira-Santos, António E Abreu, Daniela Nunes-Costa, Susana Alarico, Igor Tiago, Ana Morgadinho, João Lemos, Pedro N. Figueiredo, Cristina Januário, Nuno Empadinhas, Sandra Morais Cardoso
Format: Article
Language:English
Published: BMC 2024-10-01
Subjects:
Parkinson’s disease
Gut microbiome
Dysbiosis
Dysbiome
Innate immunity
Gut-brain axis
Online Access:https://doi.org/10.1186/s13024-024-00766-0

Internet

https://doi.org/10.1186/s13024-024-00766-0

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