Interleukin-1β mediates alterations in mitochondrial fusion/fission proteins and memory impairment induced by amyloid-β oligomers

Abstract Background The lack of effective treatments for Alzheimer’s disease (AD) reflects an incomplete understanding of disease mechanisms. Alterations in proteins involved in mitochondrial dynamics, an essential process for mitochondrial integrity and function, have been reported in AD brains. Im...

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出版年:	Journal of Neuroinflammation
主要な著者:	Andre F. Batista, Tayná Rody, Leticia Forny-Germano, Suzana Cerdeiro, Maria Bellio, Sergio T. Ferreira, Douglas P. Munoz, Fernanda G. De Felice
フォーマット:	論文
言語:	英語
出版事項:	BMC 2021-02-01
主題:	Alzheimer’s disease Mitochondrial dynamics Mitochondrial dysfunction IL-1β Neuroinflammation Aβ oligomers
オンライン･アクセス:	https://doi.org/10.1186/s12974-021-02099-x