Evaluation of somatic copy number variation detection by NGS technologies and bioinformatics tools on a hyper-diploid cancer genome

Abstract Background Copy number variation (CNV) is a key genetic characteristic for cancer diagnostics and can be used as a biomarker for the selection of therapeutic treatments. Using data sets established in our previous study, we benchmark the performance of cancer CNV calling by six most recent...

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出版年:	Genome Biology
主要な著者:	Daniall Masood, Luyao Ren, Cu Nguyen, Francesco G. Brundu, Lily Zheng, Yongmei Zhao, Erich Jaeger, Yong Li, Seong Won Cha, Aaron Halpern, Sean Truong, Michael Virata, Chunhua Yan, Qingrong Chen, Andy Pang, Reyes Alberto, Chunlin Xiao, Zhaowei Yang, Wanqiu Chen, Charles Wang, Frank Cross, Severine Catreux, Leming Shi, Julia A. Beaver, Wenming Xiao, Daoud M. Meerzaman
フォーマット:	論文
言語:	英語
出版事項:	BMC 2024-06-01
主題:	Copy number variation Cancer genome Next-generation sequencing Bioinformatics tools Consistency Accuracy
オンライン･アクセス:	https://doi.org/10.1186/s13059-024-03294-8