Sterol interactions influence the function of Wsc sensors

The Wsc1, Wsc2, and Wsc3 proteins are essential cell surface sensors that respond to cell wall perturbation by activating the cell wall integrity pathway (CWIP). We show here that in situ production of cholesterol (in place of ergosterol) induces hyper-phosphorylation of Slt2, the MAPK of the CWIP,...

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書誌詳細

出版年:	Journal of Lipid Research
主要な著者:	Lukas Bernauer, Paula Berzak, Leonie Lehmayer, Julia Messenlehner, Gustav Oberdorfer, Günther Zellnig, Heimo Wolinski, Christoph Augustin, Melanie Baeck, Anita Emmerstorfer-Augustin
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2023-12-01
主題:	Cell wall integrity Komagataella phaffii Wsc proteins sterol-binding motif MAPK signaling
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S0022227523001396