Blocking CD226 Promotes Allogeneic Transplant Immune Tolerance and Improves Skin Graft Survival by Increasing the Frequency of Regulatory T Cells in a Murine Model

Background/Aims: Regulatory T cells (Tregs) play key roles in maintaining peripheral tolerance and preventing autoimmune disease. Treg modulation could be helpful in treating malignancies, autoimmune disease, and allergies, as well as to facilitate organ transplantation. Signals transduced by co-sti...

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Bibliographic Details

Published in:	Cellular Physiology and Biochemistry
Main Authors:	Tian Liu, Dongliang Zhang, Yuan Zhang, Xiangsheng Xu, Bo Zhou, Liang Fang, Yun Zhang, Yingjun Su, Boquan Jin, Ran Zhuang, Shuzhong Guo
Format:	Article
Language:	English
Published:	Cell Physiol Biochem Press GmbH & Co KG 2018-03-01
Subjects:	CD226 Transplant immunity Treg
Online Access:	https://www.karger.com/Article/FullText/488182