Integrative greenness, blueness and whiteness determination of analytical RP-HPLC method for identifying Imipenem, Cilastatin and Relebactam in combined tablet form followed by forced degradation studies

Most clinically preferred, US FDA and EU approved anti-infective drug, a multi-component formulation of Imipenem (IPM), Cilastatin (CS) and Relebactum (REL). The combination is used in medicating the most complicated, gram-negative bacterial infections. Henceforth, it requires the development of sel...

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Bibliographic Details

Published in:	Green Analytical Chemistry
Main Authors:	Revathy Sundara Moorthy, Nakka Srisailam, Narmada Vallakeerthi, Kavitha Marapakala, P. Muralidhar Reddy
Format:	Article
Language:	English
Published:	Elsevier 2024-12-01
Subjects:	Imipenem Cilastatin Relebactum Forced degradation Green assessment Method validation
Online Access:	http://www.sciencedirect.com/science/article/pii/S2772577424000855