Brain Death in Combination with Warm Ischemic Stress during Isolation Procedures Induces the Expression of Crucial Inflammatory Mediators in the Isolated Islets

Tissue factor (TF) and monocyte chemoattractant protein-1 (MCP-1) expressed on the islets have been identified as the main trigger of the instant blood-mediated inflammatory reaction (IBMIR) in islet transplantation. Because the key steps that directly induce TF and MCP-1 remain to be determined, we...

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Bibliographic Details

Published in:	Cell Transplantation
Main Authors:	Yukihiko Saito, Masafumi Goto M.D., Ph.D., Kozue Maya, Norihiko Ogawa, Keisei Fujimori, Yoshimochi Kurokawa, Susumu Satomi
Format:	Article
Language:	English
Published:	SAGE Publishing 2010-06-01
Online Access:	https://doi.org/10.3727/096368910X508889