TGF-β Neutralization Enhances AngII-Induced Aortic Rupture and Aneurysm in Both Thoracic and Abdominal Regions.

AngII and TGF-β interact in development of thoracic and abdominal aortic diseases, although there are many facets of this interaction that have not been clearly defined. The aim of the present study was to determine the effects of TGF-β neutralization on AngII induced-aortic pathologies. Male C57BL/...

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發表在:PLoS ONE
Main Authors: Xiaofeng Chen, Debra L Rateri, Deborah A Howatt, Anju Balakrishnan, Jessica J Moorleghen, Lisa A Cassis, Alan Daugherty
格式: Article
語言:英语
出版: Public Library of Science (PLoS) 2016-01-01
在線閱讀:http://europepmc.org/articles/PMC4841552?pdf=render