Microsatellite instability and mismatch repair deficiency in bladder urothelial carcinoma: a Tunisian single-center study

Abstract Background Microsatellite instability (MSI) and deficiency in the human mismatch repair (MMR) system are critical drivers of genomic instability in various cancers. Tumors exhibiting MSI and MMR deficiency (dMMR) have prognostic implications and are associated with differential responses to...

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Bibliographic Details

Published in:	Journal of the Egyptian National Cancer Institute
Main Authors:	Ahlem Bdioui, Mariem Akkari, Maroua Krifa, Yosra Souiden, Ethmane Sleimane, Wafa Mokni, Nada Ben Lazrek, Sarra Mestiri, Sihem Hmissa, Nabiha Missaoui
Format:	Article
Language:	English
Published:	SpringerOpen 2025-05-01
Subjects:	Urothelial carcinoma Bladder DMMR MSI Immunohistochemistry PCR
Online Access:	https://doi.org/10.1186/s43046-025-00279-x