Lack of canonical thyroid hormone receptor α signaling changes regulatory T cell phenotype in female mice

Summary: The immune system has emerged as an important target of thyroid hormones (THs); however, the role of TH in T cells has so far remained elusive. In this study, we assessed the effect of TH receptor α (TRα) signaling on activation and function of T cells. Our findings show that lack of canoni...

Full description

Bibliographic Details

Published in:	iScience
Main Authors:	Christina Wenzek, Devon Siemes, G. Sebastian Hönes, Eva Pastille, Nina Härting, Frank Kaiser, Lars C. Moeller, Daniel R. Engel, Astrid M. Westendorf, Dagmar Führer
Format:	Article
Language:	English
Published:	Elsevier 2024-08-01
Subjects:	Molecular biology Immunology Endocrinology Cell biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004224017723