Chromatin profiling identifies transcriptional readthrough as a conserved mechanism for piRNA biogenesis in mosquitoes

Summary: The piRNA pathway in mosquitoes differs substantially from other model organisms, with an expanded PIWI gene family and functions in antiviral defense. Here, we define core piRNA clusters as genomic loci that show ubiquitous piRNA expression in both somatic and germline tissues. These core...

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Bibliographic Details
Published in:Cell Reports
Main Authors: Jieqiong Qu, Valerie Betting, Ruben van Iterson, Florence M. Kwaschik, Ronald P. van Rij
Format: Article
Language:English
Published: Elsevier 2023-03-01
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723002681