Hetero-antagonism of avibactam and sulbactam with cefiderocol in carbapenem-resistant Acinetobacter spp.

ABSTRACT Cefiderocol, a siderophore-cephalosporine conjugate antibiotic, shows promise as a therapeutic option for carbapenem-resistant (CR) Acinetobacter infections. While resistance has already been reported in A. baumannii, combination therapies with avibactam or sulbactam reduce MICs of cefidero...

Full description

Bibliographic Details

Published in:	Microbiology Spectrum
Main Authors:	Olivia Wong, Vyanka Mezcord, Christina Lopez, German Matias Traglia, Fernando Pasteran, Marisel R. Tuttobene, Alejandra Corso, Marcelo E. Tolmasky, Robert A. Bonomo, María Soledad Ramirez
Format:	Article
Language:	English
Published:	American Society for Microbiology 2024-10-01
Subjects:	Acinetobacter antagonism cefiderocol antimicrobial susceptibility testing (AST) avibactam sulbactam
Online Access:	https://journals.asm.org/doi/10.1128/spectrum.00930-24