NSD2 methylates AROS to promote SIRT1 activation and regulates fatty acid metabolism-mediated cancer radiotherapy

Summary: Fatty acid metabolism plays a critical role in both tumorigenesis and cancer radiotherapy. However, the regulatory mechanism of fatty acid metabolism has not been fully elucidated. NSD2, a histone methyltransferase that catalyzes di-methylation of histone H3 at lysine 36, has been shown to...

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Bibliographic Details

Published in:	Cell Reports
Main Authors:	Xun Li, Da Song, Yaqi Chen, Changsheng Huang, Anyi Liu, Qi Wu, Xiaowei She, Kangdi Li, Kairui Wan, Chengxin Yu, Cheng Qiu, Lang Liu, Guihua Wang, Feng Xu, Jing Wang, Junbo Hu
Format:	Article
Language:	English
Published:	Elsevier 2023-10-01
Subjects:	CP: Cancer CP: Metabolism
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124723011385