Precisely Tailoring Molecular Structure of Doxorubicin Prodrugs to Enable Stable Nanoassembly, Rapid Activation, and Potent Antitumor Effect

Background: Achieving a balance between stable drug loading/delivery and on-demand drug activation/release at the target sites remains a significant challenge for nanomedicines. Carrier-free prodrug nanoassemblies, which rely on the design of prodrug molecules, offer a promising strategy to optimize...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Pharmaceutics
المؤلفون الرئيسيون: Chengcheng Feng, Yuting Wang, Jiaxu Xu, Yanzi Zheng, Wenhu Zhou, Yuequan Wang, Cong Luo
التنسيق: مقال
اللغة:الإنجليزية
منشور في: MDPI AG 2024-12-01
الموضوعات:
molecular design
doxorubicin prodrug
nanoassembly
drug delivery
drug release
الوصول للمادة أونلاين:https://www.mdpi.com/1999-4923/16/12/1582

الانترنت

https://www.mdpi.com/1999-4923/16/12/1582

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