Maternal obesity blunts antimicrobial responses in fetal monocytes

Maternal pre-pregnancy (pregravid) obesity is associated with adverse outcomes for both mother and offspring. Amongst the complications for the offspring is increased susceptibility and severity of neonatal infections necessitating admission to the intensive care unit, notably bacterial sepsis and e...

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Bibliographic Details
Published in:eLife
Main Authors: Suhas Sureshchandra, Brianna M Doratt, Norma Mendza, Oleg Varlamov, Monica Rincon, Nicole E Marshall, Ilhem Messaoudi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-01-01
Subjects:
pregnancy
obesity
monocytes/macrophrages
inflammation
epigenome
transcriptome
Online Access:https://elifesciences.org/articles/81320

Internet

https://elifesciences.org/articles/81320

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