Epigenetic mechanisms of Nsd1-mediated histone methylation modifications in chondrocyte ferroptosis in knee osteoarthritis

Knee osteoarthritis (KOA) is a degenerative joint disease characterized by pain, stiffness, and impaired mobility, with current therapies offering limited efficacy. This study investigates the epigenetic role of nuclear receptor-binding SET domain protein 1 (NSD1) in KOA pathogenesis. A KOA mouse mo...

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Bibliographic Details
Published in:Biomolecules & Biomedicine
Main Authors: Rao Wang, Da Shi, Xiaoni Pan, Anqi Ren, Kai Jiang
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2024-08-01
Subjects:
Knee osteoarthritis
ferroptosis
chondrocyte
Nsd1
SOX9
ACSL4
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/10879

Internet

https://www.bjbms.org/ojs/index.php/bjbms/article/view/10879

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