Integrative analysis of serum microorganisms and serum metabolomics in osteoporosis patients based on 16S rDNA sequencing and UHPLC/MS-based metabolomics

IntroductionAlthough significant progress has been made in the treatment and research of osteoporosis patients in recent years, the genetic mechanism of osteoporosis has not yet been fully elucidated.MethodsWe conducted a comprehensive analysis using 16S sequencing and UHPLC–MS/MS metabolomics data...

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Bibliographic Details
Published in:Frontiers in Medicine
Main Authors: Yu Liu, Yun Li, Jiehua Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-09-01
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1664359/full