Generation and characterization of infectious clones of chikungunya virus from an Indian strain as a resource towards chikungunya vaccine research

India has witnessed several devastating chikungunya virus (CHIKV) epidemics since 2005. Developing a stable reverse genetic system using Indian CHIKV strains will be paramount to studying the molecular mechanism of CHIKV pathogenesis.We generated the first infectious clone (IC) of an Indian isolate...

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Bibliographic Details

Published in:	Virus Research
Main Authors:	Garvita Mathur, Shakuntala Mahilkar, Sujatha Sunil
Format:	Article
Language:	English
Published:	Elsevier 2025-06-01
Subjects:	Chikungunya virus (CHIKV) Infectious clone (IC) Genetic determinants Virus pathogenesis
Online Access:	http://www.sciencedirect.com/science/article/pii/S0168170225000486